Structural characterisation of acid- and alkali-soluble polysaccharides in the fruiting body of Dictyophora indusiata and their immunomodulatory activities

被引：51

作者：

Hua, Yanglin ^{[1
,3
]}

Gao, Qing ^{[1
]}

Wen, Lingrong ^{[1
]}

Yang, Bao ^{[2
]}

Tang, Jian ^{[3
]}

You, Lijun ^{[1
]}

Zhao, Mouming ^{[1
]}

机构：

[1] S China Univ Technol, Coll Light Ind & Food Sci, Guangzhou 510640, Guangdong, Peoples R China

[2] Chinese Acad Sci, S China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China

[3] Infinitus China Co Ltd, Guangzhou 510665, Guangdong, Peoples R China

来源：

FOOD CHEMISTRY | 2012年 / 132卷 / 02期

基金：

中国国家自然科学基金;

关键词：

GC/MS; Immunomodulatory activity; Dictyophora indusiata; Polysaccharide; MEDICINAL MUSHROOMS; ANTITUMOR-ACTIVITY; ANTIOXIDANT;

D O I：

10.1016/j.foodchem.2011.11.010

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

The acid- and alkali-soluble polysaccharides (DIPs I and II) were extracted from the fruiting body of Dictyophora indusiata in this work. DIP I comprised of Glc (glucose), Fru (fructose) and Man (mannose), whereas DIP II was of Glc and Fru. Glc was the dominant monosaccharide in both DIPs with relatively molar percentage of >60%, which constructed the backbone of polysaccharide chain. The analysis of the glycosidic linkages indicated that Glc occurred as Glc 1 -> 6 in DIP II. The immunological assays showed that both DIPs I and II had a noticeable effect on the hemolysis antibody level in the tested dosage range. However, DIP I could improve the weight of thymus organ and phagocytosis of monocyte. DIP II could restore delayed-type hypersensitivity reaction to dinitrofluorobenzene (DNFB). improving the activity of natural killer cells and the proliferation of splenocytes at high dose. (C) 2011 Elsevier Ltd. All rights reserved.

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收藏

页码：739 / 743

页数：5

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