On-line laser photoacoustic detection of ethene in exhaled air as biomarker of ultraviolet radiation damage of the human skin

被引：68

作者：

Harren, FJM ^{[1
]}

Berkelmans, R

Kuiper, K

Hekkert, ST

Scheepers, P

Dekhuijzen, R

Hollander, P

Parker, DH

机构：

[1] Univ Nijmegen, Dept Mol & Laser Phys, Nijmegen, Netherlands

[2] Free Univ Amsterdam, Dept Kinesiol, Amsterdam, Netherlands

[3] Univ Nijmegen, Dept Toxicol, Nijmegen, Netherlands

[4] Acad Hosp, Dept Pulm Dis, Nijmegen, Netherlands

来源：

APPLIED PHYSICS LETTERS | 1999年 / 74卷 / 12期

关键词：

D O I：

10.1063/1.123680

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The exhaled air and volatile emission by the skin of human subjects were analyzed for traces of ethene (C2H4) by means of CO2 laser photoacoustic trace gas detection. Due to the extreme sensitivity of the detection system (6 part per trillion volume, 6: 10(12)), these measurements could be performed on-line and noninvasively. Exhaled ethene was used as a biomarker for lipid peroxidation in the skin of human subjects exposed to ultraviolet (UV) radiation from a solarium. A change in the ethene concentration was already observed in the exhaled air after 2 min. Adaptation of the skin to UV exposure and direct skin emission could also be observed. (C) 1999 American Institute of Physics. [S0003-6951(99)01312-1].

引用

页码：1761 / 1763

页数：3

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