Adventures in inner space: Microflow systems for practical organic synthesis

被引：305

作者：

Fukuyama, Takahide ^{[1
]}

Rahman, Taifur ^{[1
]}

Sato, Masaaki ^{[1
]}

Ryu, Ilhyong ^{[1
]}

机构：

[1] Osaka Prefecture Univ, Fac Sci, Dept Chem, Sakai, Osaka 5998531, Japan

来源：

SYNLETT | 2008年 / 02期

关键词：

microreactor; cross-coupling reaction; carbonylation; hydrogenation; photoreaction; ionic liquid; continuous production system;

D O I：

10.1055/s-2007-1000884

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This account presents an overview of our recent endeavors to achieve practical organic syntheses using a variety of microreaction devices. Herein are our achievements in ionic liquid-based catalytic reactions, photochemical transformation, and heterogenous hydrogenation reactions, where flow regime precisely controls residence time and product selectivity. 1, Introduction 2 Cross-Coupling Reactions Using Ionic Liquids and Microflow Systems 2.1 The Sonogashira Coupling Reaction in a Microreaction System 2.2 The Mizoroki-Heck Reaction in an Automated Microflow Production System 2.3 Carbonylation in an Ionic Liquid and Application to a Microflow System 3 Photo- and Radical Reactions in a Microflow System 4 Gas-Liquid-Solid Triphasic Catalytic Reactions in a Microflow System 5 Conclusion.

引用

页码：151 / 163

页数：13

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