Method for Phenotypic Detection of Extended-Spectrum Beta-Lactamases in Enterobacter Species in the Routine Clinical Setting

被引:10
作者
Stuart, James Cohen [1 ]
Diederen, Bram [2 ]
al Naiemi, Nashwan [3 ]
Fluit, Ad [1 ]
Arents, Niek [4 ]
Thijsen, Steven [5 ]
Vlaminckx, Bart [6 ]
Mouton, Johan W. [7 ]
Leverstein-van Hall, Maurine [1 ,8 ]
机构
[1] Univ Med Ctr Utrecht, Dept Med Microbiol, NL-3584 CX Utrecht, Netherlands
[2] Reg Lab Publ Hlth Haarlem, Haarlem, Netherlands
[3] Vrije Univ Amsterdam Med Ctr, Dept Med Microbiol & Infect Control, Amsterdam, Netherlands
[4] Labs Pathol Anat & Med Microbiol Veldhoven, Veldhoven, Netherlands
[5] Diakonessenhuis Utrecht, Dept Med Microbiol & Immunol, Utrecht, Netherlands
[6] St Antonius Hosp, Dept Med Microbiol & Immunol, Nieuwegein, Netherlands
[7] Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, NL-6525 ED Nijmegen, Netherlands
[8] Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Bilthoven, Netherlands
关键词
CLOACAE; RESISTANCE; CEFEPIME; SHV; EMERGENCE; OUTBREAK;
D O I
10.1128/JCM.00864-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In 271 Enterobacter blood culture isolates from 12 hospitals, extended-spectrum beta-lactamase (ESBL) prevalence varied between 0% and 30% per hospital. High prevalence was associated with dissemination, indicating the potential relevance of infection control measures. Screening with cefepime or Vitek 2, followed by a cefepime/cefepime-clavulanate Etest, was an accurate strategy for ESBL detection in Enterobacter isolates (positive predictive value, 100%; negative predictive value, 99%).
引用
收藏
页码:2711 / 2713
页数:3
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