The cyclohexene ring as bioisostere of a furanose ring: Synthesis and antiviral activity of cyclohexenyl nucleosides

被引：48

作者：

Herdewijn, P

De Clercq, E

机构：

[1] Katholieke Univ Leuven, Rega Inst Med Res, Med Chem Lab, B-3000 Louvain, Belgium

[2] Katholieke Univ Leuven, Rega Inst Med Res, Lab Antiviral Chemotherapy, B-3000 Louvain, Belgium

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2001年 / 11卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(01)00270-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The application of the bioisosteric concept between a furanose ring and a cyclohexene ring in the nucleoside field has led to the discovery of new potent antiviral agents. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：1591 / 1597

页数：7

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