Efficient one-step synthesis of optically pure (adenin-8-yl)phenylalanine nucleosides

被引：22

作者：

Capek, P ^{[1
]}

Hocek, M ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Organ Chem & Biochem, Ctr New Antivirals & Antineoplast, Prague 16610 6, Czech Republic

来源：

SYNLETT | 2005年 / 19期

关键词：

cross-coupling; purines; nucleosides; palladium; amino acids;

D O I：

10.1055/s-2005-921896

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient single-step synthesis of optically pure (adenin-8-yl)phenylalanine nucleosides, a new type of purine amino acid conjugate, by palladium-catalyzed cross-coupling reactions of unprotected 8-bromoadenosines with 4-(borono)phenylaianine was developed.

引用

页码：3005 / 3007

页数：3

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