Outgrowth Endothelial Cells: Sources, Characteristics and Potential Applications in Tissue Engineering and Regenerative Medicine

被引：39

作者：

Fuchs, Sabine ^{[1
]}

Dohle, Eva ^{[1
]}

Kolbe, Marlen ^{[1
]}

Kirkpatrick, Charles James ^{[1
]}

机构：

[1] Univ Med Johannes Gutenberg Univ, Inst Pathol, Mainz, Germany

来源：

BIOREACTOR SYSTEMS FOR TISSUE ENGINEERING II: STRATEGIES FOR THE EXPANISON AND DIRECTED DIFFERENTIATION OF STEM CELLS | 2010年 / 123卷

关键词：

Bone tissue engineering; Co-culture models; Endothelial progenitor cells; Vascularization; HUMAN PERIPHERAL-BLOOD; MESENCHYMAL STEM-CELLS; PROGENITOR CELLS; GROWTH-FACTOR; IN-VITRO; HUMAN OSTEOPROGENITORS; GENE-EXPRESSION; SONIC HEDGEHOG; CORD BLOOD; DIFFERENTIATION;

D O I：

10.1007/10_2009_65

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Endothelial progenitor cells from peripheral blood or cord blood are attracting increasing interest as a potential cell source for cellular therapies aiming to enhance the neovascularization of tissue engineered constructs or ischemic tissues. The present review focus on a specific population contained in endothelial progenitor cell cultures designated as outgrowth endothelial cells (OEC) or endothelial colony forming cells from peripheral blood or cord blood. Special attention will be paid to what is currently known in terms of the origin and the cell biological or functional characteristics of OEC. Furthermore, we will discuss current concepts, how OEC might be integrated in complex tissue engineered constructs based on biomaterial or co-cultures, with special emphasis on their potential application in bone tissue engineering and related vascularization strategies.

引用

页码：201 / 217

页数：17

共 84 条

[31] Human primary endothelial cells stimulate human osteoprogenitor cell differentiation [J].

Guillotin, B ;

Bourget, C ;

Remy-Zolgadri, M ;

Bareille, R ;

Fernandez, P ;

Conrad, V ;

Amédée-Vilamitjana, J .

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2004, 14 (4-6) :325-332

[32] Diverse origin and function of cells with endothelial phenotype obtained from adult human blood [J].

Gulati, R ;

Jevremovic, D ;

Peterson, TE ;

Chatterjee, S ;

Shah, V ;

Vile, RG ;

Simari, RD .

CIRCULATION RESEARCH, 2003, 93 (11) :1023-1025

[33] Immobilized DNA aptamers used as potent attractors for porcine endothelial precursor cells [J].

Hoffmann, Jan ;

Paul, Angela ;

Harwardt, Marc ;

Groll, Juergen ;

Reeswinkel, Thomas ;

Klee, Doris ;

Moeller, Martin ;

Fischer, Heike ;

Walker, Tobias ;

Greiner, Tim ;

Ziemer, Gerhard ;

Wendel, Hans P. .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2008, 84A (03) :614-621

[34] The effect of human osteoblasts on proliferation and neo-vessel formation of human umbilical vein endothelial cells in a long-term 3D co-culture on polyurethane scaffolds [J].

Hofmann, Alexander ;

Ritz, Ulrike ;

Verrier, Sophie ;

Eglin, David ;

Alini, Mauro ;

Fuchs, Sabine ;

Kirkpatrick, C. James ;

Rommens, Pol Maria .

BIOMATERIALS, 2008, 29 (31) :4217-4226

[35] Regulation of endothelial progenitor cell homing after arterial injury [J].

Hristov, Mihail ;

Zernecke, Alma ;

Liehn, Elisa A. ;

Weber, Christian .

THROMBOSIS AND HAEMOSTASIS, 2007, 98 (02) :274-277

[36] Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis [J].

Hur, J ;

Yoon, CH ;

Kim, HS ;

Choi, JH ;

Kang, HJ ;

Hwang, KK ;

Oh, BH ;

Lee, MM ;

Park, YB .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (02) :288-293

[37] Vessel wall-derived endothelial cells rapidly proliferate because they contain a complete hierarchy of endothelial progenitor cells [J].

Ingram, DA ;

Mead, LE ;

Moore, DB ;

Woodard, W ;

Fenoglio, A ;

Yoder, MC .

BLOOD, 2005, 105 (07) :2783-2786

[38] Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood [J].

Ingram, DA ;

Mead, LE ;

Tanaka, H ;

Meade, V ;

Fenoglio, A ;

Mortell, K ;

Pollok, K ;

Ferkowicz, MJ ;

Gilley, D ;

Yoder, MC .

BLOOD, 2004, 104 (09) :2752-2760

[39]

Jiang Aixiang, 2007, J Bioinform Comput Biol, V5, P875, DOI 10.1142/S0219720007002989

[40] Role of vascular endothelial growth factor in bone marrow stromal cell modulation of endothelial cells [J].

Kaigler, D ;

Krebsbach, PH ;

Polverini, PJ ;

Mooney, DJ .

TISSUE ENGINEERING, 2003, 9 (01) :95-103

← 1 2 3 4 5 6 7 8 9 →