SINEs point to abundant editing in the human genome

被引：21

作者：

DeCerbo, J ^{[1
]}

Carmichael, GG ^{[1
]}

机构：

[1] Univ Connecticut, Ctr Hlth, Dept Genet & Dev Biol, Farmington, CT 06030 USA

来源：

GENOME BIOLOGY | 2005年 / 6卷 / 04期

关键词：

D O I：

10.1186/gb-2005-6-4-216

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Recent bioinformatic analyses suggest that almost all human transcripts are edited by adenosine deaminases (ADARs), converting adenosines to inosines. Most of this editing is in Alu element transcripts, which are unique to primates. This editing might have no function or might be involved in functions such as the regulation of splicing, chromatin or nuclear localization of transcripts.

引用

页数：4

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