Ran in the spindle checkpoint: a new function for a versatile GTPase

被引：27

作者：

Li, HY

Cao, K

Zheng, YX

机构：

[1] Carnegie Inst Sci, Dept Embryol, Baltimore, MD 21210 USA

[2] Johns Hopkins Univ, Howard Hughes Med Inst, Baltimore, MD 21210 USA

[3] Johns Hopkins Univ, Dept Biol, Baltimore, MD 21210 USA

来源：

TRENDS IN CELL BIOLOGY | 2003年 / 13卷 / 11期

关键词：

NUCLEOCYTOPLASMIC TRANSPORT; MICROTUBULE ASTERS; MITOTIC CHECKPOINT; IMPORTIN-BETA; DYNAMICS; RCC1;

D O I：

10.1016/j.tcb.2003.09.003

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The small GTPase Ran has a well-established role in nucleocytoplasmic trafficking. In recent years, the repertoire of Ran has expanded to include regulation of spindle assembly, formation of the nuclear envelope and DNA replication. Now, new studies further extend the role of Ran to regulating the spindle checkpoint during mitosis.

引用

页码：553 / 557

页数：5

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