Synthesis of complex carbohydrates and glycoconjugates: Enzyme-based and programmable one-pot strategies

被引：407

作者：

Koeller, KM

Wong, CH

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

CHEMICAL REVIEWS | 2000年 / 100卷 / 12期

关键词：

D O I：

10.1021/cr990297n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review describes recent advances in enzymatic and chemical methods for the facile generation of complex oligosaccharides and glycoconjugates. It is emphasized that glycosylation remains one of the most poorly understood postranslational modifications, although general themes in glycoconjugate function are slowly emerging.

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页码：4465 / 4493

页数：29

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