Palladium-catalyzed addition of alcohol pronucleophiles to alkylidenecyclopropanes

被引：100

作者：

Camacho, DH

Nakamura, I

Saito, S

Yamamoto, Y ^{[1
]}

机构：

[1] Tohoku Univ, Dept Chem, Grad Sch Sci, Sendai, Miyagi 9808578, Japan

[2] Tohoku Univ, Inst Chem React Sci, Sendai, Miyagi 9808578, Japan

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2001年 / 66卷 / 01期

关键词：

D O I：

10.1021/jo001428j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed addition of alcohol pronucleophiles 1 to alkylidenecyclopropane derivatives 2 afforded the corresponding allylic ethers 3 in excellent to moderate yields. Catalyst optimization indicated the Pd(PPh3)(4)-P(o-tolyl)(3) combination as the best system among all catalysts tested. Intramolecular reaction also proceeded smoothly. A plausible mechanism for this catalytic reaction was proposed.

引用

页码：270 / 275

页数：6

共 57 条

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