Genetic tests for common diseases: new insights, old concerns

被引：36

作者：

Melzer, David ^{[1
]}

Hogarth, Stuart ^{[2
]}

Liddell, Katherine ^{[3
]}

Ling, Tom ^{[4
]}

Sanderson, Simon ^{[5
]}

Zimmern, Ron L. ^{[5
]}

机构：

[1] Univ Exeter, Peninsula Med Sch, Exeter EX1 2LU, Devon, England

[2] Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge CB2 1TN, England

[3] Univ Cambridge, Cambridge Fac Law, Cambridge CB2 1TN, England

[4] RAND Europe, Cambridge, England

[5] PHG Fdn, Cambridge, England

来源：

BRITISH MEDICAL JOURNAL | 2008年 / 336卷 / 7644期

基金：

英国惠康基金;

关键词：

D O I：

10.1136/bmj.39506.601053.BE

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：590 / 593

页数：6

共 24 条

[1] Guilt beyond a reasonable doubt [J].

Altshuler, David ;

Daly, Mark .

NATURE GENETICS, 2007, 39 (07) :813-815

[2] Toward a major risk factor for atopic eczema:: Meta-analysis of filaggrin polymorphism data [J].

Baurecht, Hansjoerg ;

Irvine, Alan D. ;

Novak, Natalija ;

Illig, Thomas ;

Buehler, Bettina ;

Ring, Johannes ;

Wagenpfeil, Stefan ;

Weidinger, Stephan .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (06) :1406-1412

[3] Future use of genomics in coronary artery disease [J].

Damani, Samir B. ;

Topol, Eric J. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 50 (20) :1933-1940

[4] The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies [J].

De Silva, N. M. G. ;

Steele, A. ;

Shields, B. ;

Knight, B. ;

Parnell, K. ;

Weedon, M. N. ;

Hattersley, A. T. ;

Frayling, T. M. .

DIABETIC MEDICINE, 2007, 24 (10) :1067-1072

[5] Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease - A meta-analysis [J].

Farrer, LA ;

Cupples, LA ;

Haines, JL ;

Hyman, B ;

Kukull, WA ;

Mayeux, R ;

Myers, RH ;

PericakVance, MA ;

Risch, N ;

vanDuijn, CM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (16) :1349-1356

[6] The common biology of cancer and ageing [J].

Finkel, Toren ;

Serrano, Manuel ;

Blasco, Maria A. .

NATURE, 2007, 448 (7155) :767-774

[7] A second generation human haplotype map of over 3.1 million SNPs [J].

Frazer, Kelly A. ;

Ballinger, Dennis G. ;

Cox, David R. ;

Hinds, David A. ;

Stuve, Laura L. ;

Gibbs, Richard A. ;

Belmont, John W. ;

Boudreau, Andrew ;

Hardenbol, Paul ;

Leal, Suzanne M. ;

Pasternak, Shiran ;

Wheeler, David A. ;

Willis, Thomas D. ;

Yu, Fuli ;

Yang, Huanming ;

Zeng, Changqing ;

Gao, Yang ;

Hu, Haoran ;

Hu, Weitao ;

Li, Chaohua ;

Lin, Wei ;

Liu, Siqi ;

Pan, Hao ;

Tang, Xiaoli ;

Wang, Jian ;

Wang, Wei ;

Yu, Jun ;

Zhang, Bo ;

Zhang, Qingrun ;

Zhao, Hongbin ;

Zhao, Hui ;

Zhou, Jun ;

Gabriel, Stacey B. ;

Barry, Rachel ;

Blumenstiel, Brendan ;

Camargo, Amy ;

Defelice, Matthew ;

Faggart, Maura ;

Goyette, Mary ;

Gupta, Supriya ;

Moore, Jamie ;

Nguyen, Huy ;

Onofrio, Robert C. ;

Parkin, Melissa ;

Roy, Jessica ;

Stahl, Erich ;

Winchester, Ellen ;

Ziaugra, Liuda ;

Altshuler, David ;

Shen, Yan .

NATURE, 2007, 449 (7164) :851-U3

[8]

HARMON A, 2007, NY TIMES 1117

[9] A common variant on chromosome 9p21 affects the risk of myocardial infarction [J].

Helgadottir, Anna ;

Thorleifsson, Gudmar ;

Manolescu, Andrei ;

Gretarsdottir, Solveig ;

Blondal, Thorarinn ;

Jonasdottir, Aslaug ;

Jonasdottir, Adalbjorg ;

Sigurdsson, Asgeir ;

Baker, Adam ;

Palsson, Arnar ;

Masson, Gisli ;

Gudbjartsson, Daniel F. ;

Magnusson, Kristinn P. ;

Andersen, Karl ;

Levey, Allan I. ;

Backman, Valgerdur M. ;

Matthiasdottir, Sigurborg ;

Jonsdottir, Thorbjorg ;

Palsson, Stefan ;

Einarsdottir, Helga ;

Gunnarsdottir, Steinunn ;

Gylfason, Arnaldur ;

Vaccarino, Viola ;

Hooper, W. Craig ;

Reilly, Muredach P. ;

Granger, Christopher B. ;

Austin, Harland ;

Rader, Daniel J. ;

Shah, Svati H. ;

Quyyumi, Arshed A. ;

Gulcher, Jeffrey R. ;

Thorgeirsson, Gudmundur ;

Thorsteinsdottir, Unnur ;

Kong, Augustine ;

Stefansson, Kari .

SCIENCE, 2007, 316 (5830) :1491-1493

[10]

Hogarth S, 2007, FOOD DRUG LAW J, V62, P831

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