Pharyngeal mesoderm development during embryogenesis: implications for both heart and head myogenesis

被引:61
作者
Tzahor, Eldad [1 ]
Evans, Sylvia M. [2 ]
机构
[1] Weizmann Inst Sci, Dept Biol Regulat, IL-76100 Rehovot, Israel
[2] Univ Calif San Diego, Skaggs Sch Pharm, La Jolla, CA 92093 USA
基金
以色列科学基金会;
关键词
Heart; Head muscle; Pharyngeal mesoderm; NEURAL CREST CELLS; CARDIAC OUTFLOW TRACT; MUSCLE DEVELOPMENT; ARTERIAL POLE; 2ND HEART; CIONA-INTESTINALIS; FIELD DEVELOPMENT; PROGENITOR CELLS; CARDIOVASCULAR PROGENITORS; CRANIOFACIAL MYOGENESIS;
D O I
10.1093/cvr/cvr116
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
The pharyngeal mesoderm (PM), located in the head region of the developing embryo, recently triggered renewed interest as the major source of cells contributing to broad regions of the heart as well as to the head musculature. What exactly is PM? In this review, we describe the anatomical and molecular characteristics of this mesodermal population and its relationship to the first and second heart fields in chick and mouse embryos. The regulatory network of transcription factors and signalling molecules that regulate PM development is also discussed. In addition, we summarize recent studies into the evolutionary origins of this tissue and its multipotential contributions to both cardiac and pharyngeal muscle progenitors.
引用
收藏
页码:196 / 202
页数:7
相关论文
共 70 条
[51]
The ascidian Mesp gene specifies heart precursor cells [J].
Satou, Y ;
Imai, KS ;
Satoh, N .
DEVELOPMENT, 2004, 131 (11) :2533-2541
[52]
Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch [J].
Shih, Hung Ping ;
Gross, Michael K. ;
Kioussi, Chrissa .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (14) :5907-5912
[53]
Early Chordate Origins of the Vertebrate Second Heart Field [J].
Stolfi, Alberto ;
Gainous, T. Blair ;
Young, John J. ;
Mori, Alessandro ;
Levine, Michael ;
Christiaen, Lionel .
SCIENCE, 2010, 329 (5991) :565-568
[54]
Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells [J].
Sun, Yunfu ;
Liang, Xingqun ;
Najafi, Nader ;
Cass, Margaret ;
Lin, Lizhu ;
Cai, Chen-Leng ;
Chen, Ju ;
Evans, Sylvia M. .
DEVELOPMENTAL BIOLOGY, 2007, 304 (01) :286-296
[55]
Mesoderm progenitor cells of common origin contribute to the head musculature and the cardiac outflow tract [J].
Tirosh-Finkel, L ;
Elhanany, H ;
Rinon, A ;
Tzahor, E .
DEVELOPMENT, 2006, 133 (10) :1943-1953
[56]
BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors [J].
Tirosh-Finkel, Libbat ;
Zeisel, Amit ;
Brodt-Ivenshitz, Miriam ;
Shamai, Ayelet ;
Yao, Zhong ;
Seger, Rony ;
Domany, Eytan ;
Tzahor, Eldad .
DEVELOPMENT, 2010, 137 (18) :2989-3000
[57]
Developmental origins of species-specific muscle pattern [J].
Tokita, Masayoshi ;
Schneider, Richard A. .
DEVELOPMENTAL BIOLOGY, 2009, 331 (02) :311-325
[58]
Wnt signals from the neural tube block ectopic cardiogenesis [J].
Tzahor, E ;
Lassar, AB .
GENES & DEVELOPMENT, 2001, 15 (03) :255-260
[59]
Antagonists of Wnt and BMP signaling promote the formation of vertebrate head muscle [J].
Tzahor, E ;
Kempf, H ;
Mootoosamy, RC ;
Poon, AC ;
Abzhanov, A ;
Tabin, CJ ;
Dietrich, S ;
Lassar, AB .
GENES & DEVELOPMENT, 2003, 17 (24) :3087-3099
[60]
Wnt/β-catenin signaling and cardiogenesis:: Timing does matter [J].
Tzahor, Eldad .
DEVELOPMENTAL CELL, 2007, 13 (01) :10-13