An IrI-catalyzed exo-selective tandem cycloisomerization/hydroalkoxylation of bis-homopropargylic alcohols at room temperature

被引：89

作者：

Genin, E ^{[1
]}

Antoniotti, S ^{[1
]}

Michelet, V ^{[1
]}

Genet, JP ^{[1
]}

机构：

[1] ENSCP, Lab Synth Select Organ & Prod Nat, UMR 7573, F-75231 Paris, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 31期

关键词：

atom economy; cyclization; homogeneous catalysis; iridium; tandem reaction;

D O I：

10.1002/anie.200501150

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) An efficient, selective, and atom-economical access to ketal building blocks is provided by the title reaction (see scheme). The entire process occurs smoothly in the presence of a catalytic amount of [{lr(cod)Cl}2] at room temperature in methanol, ethanol, or allyl alcohol as solvents. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4949 / 4953

页数：5

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