Microwave-accelerated methodology for the direct reductive amination of aldehydes

被引：39

作者：

Kangasmetsa, JJ ^{[1
]}

Johnson, T ^{[1
]}

机构：

[1] Medivir UK Ltd, Saffron Walden CB10 1XL, Essex, England

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 25期

关键词：

D O I：

10.1021/ol0522844

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] An improved procedure for the direct reductive amination of aldehydes was developed which uses dibutyltin dichloride as catalyst in the presence of phenylsilane as reductant. Rapid reaction is promoted by the use of microwave conditions with anilines, secondary and primary amines being suitable reactants.

引用

页码：5653 / 5655

页数：3

共 19 条

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