Single-step stereoselective synthesis of (E)- and (Z)-allylamines from acetyl derivatives of Baylis-Hillman adducts

被引：22

作者：

Das, B ^{[1
]}

Mahender, G ^{[1
]}

Chowdhury, N ^{[1
]}

Banerjee, J ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Chem Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNLETT | 2005年 / 06期

关键词：

allylamine; Baylis-Hillman adduct; acetyl derivative; NH4OAc; stereochemistry;

D O I：

10.1055/s-2005-864822

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereoselective synthesis of (E)- and (Z)-allylamines has been achieved in a single-step by treatment of the acetyl derivatives of Baylis-Hillman adducts with ammonium acetate in anhydrous methanol at room temperature. The reaction proceeded under neutral conditions to form the corresponding allylamines in high yields and stereoselectivity.

引用

页码：1000 / 1002

页数：3

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