Combined metal catalysis and biocatalysis for an efficient deracemization process

被引：47

作者：

Pàmies, O ^{[1
]}

Bäckvall, JE ^{[1
]}

机构：

[1] Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2003年 / 14卷 / 04期

关键词：

D O I：

10.1016/S0958-1669(03)00097-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Driven by the demand to enhance the economic balance of chemical processes, the transformation of a racemate into a single stereoisomer (the deracemization process) is one of the most important areas of research. The recent development of the combined use of enzyme and metal catalysis has led to efficient deracemization processes. Dynamic kinetic resolution and cyclic deracemization processes have shown particular promise in this area.

引用

页码：407 / 413

页数：7

共 44 条

[1] Amine-boranes:: effective reducing agents for the deracemisation of DL-amino acids using L-amino acid oxidase from Proteus myxofaciens [J].

Alexandre, FR ;

Pantaleone, DP ;

Taylor, PP ;

Fotheringham, IG ;

Ager, DJ ;

Turner, NJ .

TETRAHEDRON LETTERS, 2002, 43 (04) :707-710

[2]

Alexeeva M, 2002, ANGEW CHEM INT EDIT, V41, P3177, DOI 10.1002/1521-3773(20020902)41:17<3177::AID-ANIE3177>3.0.CO

[3]

2-P

[4] Deracemisation and stereoinversion of α-amino acids using D-amino acid oxidase and hydride reducing agents [J].

Beard, TM ;

Turner, NJ .

CHEMICAL COMMUNICATIONS, 2002, (03) :246-247

[5]

Carrea G, 2000, ANGEW CHEM INT EDIT, V39, P2226

[6]

Choi JH, 2002, ANGEW CHEM INT EDIT, V41, P2373, DOI 10.1002/1521-3773(20020703)41:13<2373::AID-ANIE2373>3.0.CO

[7]

2-7

[8] Efficient ruthenium-catalyzed racemization of secondary alcohols: application to dynamic kinetic resolution [J].

Dijksman, A ;

Elzinga, JM ;

Li, YX ;

Arends, IWCE ;

Sheldon, RA .

TETRAHEDRON-ASYMMETRY, 2002, 13 (08) :879-884

[9] Catalytic racemisation of alcohols: Applications to enzymatic resolution reactions [J].

Dinh, PM ;

Howarth, JA ;

Hudnott, AR ;

Williams, JMJ ;

Harris, W .

TETRAHEDRON LETTERS, 1996, 37 (42) :7623-7626

[10] Controlled racemization of optically active organic compounds: Prospects for asymmetric transformation [J].

Ebbers, EJ ;

Ariaans, GJA ;

Houbiers, JPM ;

Bruggink, A ;

Zwanenburg, B .

TETRAHEDRON, 1997, 53 (28) :9417-9476

← 1 2 3 4 5 →