Recent advances on cyclins, CDKs and CDK inhibitors

被引：46

作者：

Martin-Castellanos, C

Moreno, S

机构：

[1] Inst. de Microbiologia Bioquimica, Depto. de Microbiologia y Genetica, Universidad de Salamanca

来源：

TRENDS IN CELL BIOLOGY | 1997年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0962-8924(96)10055-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In eukaryotes, cell division is controlled by cyclin-dependent kinases (CDKs). Here we summarize a few new developments on the regulation of the cell cycle by CDK-cyclin complexes. We have focused on three aspects in which there has been recent progress: the structural analysis of these complexes, the phenotypes of mice carrying knockouts of CDK inhibitors and the role of proteolysis in the regulation of the cell cycle.

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页码：95 / 98

页数：4

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