Molecular genetics of uveal melanoma

被引：18

作者：

Loercher, AE ^{[1
]}

Harbour, JW ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Ophthalmol & Visual Sci, St Louis, MO 63110 USA

来源：

CURRENT EYE RESEARCH | 2003年 / 27卷 / 02期

关键词：

D O I：

10.1076/ceyr.27.2.69.15952

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

In the past decade, there have been impressive advances in our understanding of chromosomal, genetic and molecular alterations that occur in uveal melanoma. Nevertheless, a coherent picture of the molecular pathogenesis of this eye cancer is yet to emerge. Herein, we review the findings to date, discuss the insights they provide, and suggest future directions for molecular research in uveal melanoma.

引用

页码：69 / 74

页数：6

共 52 条

[21] Prevalence of the BRCA2 6174 del T mutation in Israeli uveal melanoma patients [J].

Iscovich, J ;

Abdulrazik, M ;

Cour, C ;

Fischbein, A ;

Pe'er, J ;

Goldgar, DE .

INTERNATIONAL JOURNAL OF CANCER, 2002, 98 (01) :42-44

[22]

Janssen K, 1996, MODERN PATHOL, V9, P267

[23]

Jay V, 1996, ARCH PATHOL LAB MED, V120, P497

[24]

Landers JE, 1997, CANCER RES, V57, P3562

[25] Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability [J].

McGill, GG ;

Horstmann, M ;

Widlund, HR ;

Du, JY ;

Motyckova, G ;

Nishimura, EK ;

Lin, YL ;

Ramaswamy, S ;

Avery, W ;

Ding, HF ;

Jordan, SA ;

Jackson, IJ ;

Korsmeyer, SJ ;

Golub, TR ;

Fisher, DE .

CELL, 2002, 109 (06) :707-718

[26]

Merbs SL, 1999, INVEST OPHTH VIS SCI, V40, P779

[27]

Myatt N, 2000, J PATHOL, V192, P511

[28]

Naus NC, 2001, GENE CHROMOSOME CANC, V30, P267, DOI 10.1002/1098-2264(2000)9999:9999<::AID-GCC1088>3.0.CO

[29]

2-7

[30] New perspectives for tumor pathology provided by comparative genomic hybridization [J].

Oga A. ;

Kawauchi S. ;

Izumi H. ;

Ping L.X. ;

Furuya T. ;

Sasaki K. .

International Journal of Clinical Oncology, 2002, 7 (3) :133-137

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