Chemical processing on microchips for analysis, synthesis, and bioassay

被引:43
作者
Tokeshi, M
Kikutani, Y
Hibara, A
Sato, K
Hisamoto, H
Kitamori, T
机构
[1] Univ Tokyo, Sch Engn, Dept Appl Chem, Bunkyo Ku, Tokyo 1138656, Japan
[2] Kanagawa Acad Sci & Technol, Integrated Chem Project, Kanagawa, Japan
[3] Univ Tokyo, Sch Agr & Life Sci, Dept Appl Biol Chem, Tokyo, Japan
[4] Himeji Inst Technol, Grad Sch, Dept Mat Sci, Himeji, Hyogo 67122, Japan
[5] Himeji Inst Technol, Fac Sci, Himeji, Hyogo 67122, Japan
关键词
continuous-flow chemical processing; microunit operation; miniaturization; multiphase laminar flow; pressure-driven flow; review; thermal lens microscope;
D O I
10.1002/elps.200305661
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This review describes our recent research on miniaturization of chemical systems. We have developed a miniaturization methodology based on pressure-driven multiphase laminar flow and a highly sensitive detection tool, the thermal lens microscope. Some representative applications of the methodology in the fields of analysis, synthesis, and bioassay are described.
引用
收藏
页码:3583 / 3594
页数:12
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