A novel and expeditious route to A-81988: An angiotensin II receptor antagonist

被引：5

作者：

Kerdesky, FAJ

Sowin, TJ

机构：

[1] Process Research, Pharmaceutical Products Division, Abbott Laboratories, North Chicago

来源：

SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 05期

关键词：

D O I：

10.1080/00397919608003705

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient synthesis of A-81988, an angiotensin II receptor antagonist, is described. The key step utilizes a palladium-catalyzed biaryl coupling between a phenylboronic acid derivative and N-trityl-5-(2-bromophenyl)tetrazole.

引用

页码：1007 / 1013

页数：7

共 7 条

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