DEAD-box RNA helicase p68 is not required for nuclear translocation of β-catenin in colon cancer cells

被引:8
作者
Stucke, Volker M. [1 ]
Gorses, Delphine [1 ]
Hofmann, Francesco [1 ]
机构
[1] Novartis Pharma AG, Novartis Inst BioMed Res, Dis Area Oncol, CH-4002 Basel, Switzerland
关键词
colon cancer; Wnt signaling; beta-catenin; nuclear transport; cell proliferation;
D O I
10.4161/cc.7.6.5614
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:830 / 832
页数:3
相关论文
共 15 条
[1]   Mining the Wnt pathway for cancer therapeutics [J].
Barker, Nick ;
Clevers, Hans .
NATURE REVIEWS DRUG DISCOVERY, 2006, 5 (12) :997-1014
[2]   Wnt/β-catenin signaling in development and disease [J].
Clevers, Hans .
CELL, 2006, 127 (03) :469-480
[3]   Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of β-catenin [J].
Fagotto, F ;
Glück, U ;
Gumbiner, BM .
CURRENT BIOLOGY, 1998, 8 (04) :181-190
[4]   In vivo antitumor activity of NVP-AEW541 -: A novel, potent, and selective inhibitor of the IGF-IR kinase [J].
García-Echeverría, C ;
Pearson, MA ;
Marti, A ;
Meyer, T ;
Mestan, J ;
Zimmermann, J ;
Gao, JP ;
Brueggen, J ;
Capraro, HG ;
Cozens, R ;
Evans, DB ;
Fabbro, D ;
Furet, P ;
Porta, DG ;
Liebetanz, J ;
Martiny-Baron, G ;
Ruetz, S ;
Hofmann, F .
CANCER CELL, 2004, 5 (03) :231-239
[5]   IDENTIFICATION OF FAP LOCUS GENES FROM CHROMOSOME-5Q21 [J].
KINZLER, KW ;
NILBERT, MC ;
SU, LK ;
VOGELSTEIN, B ;
BRYAN, TM ;
LEVY, DB ;
SMITH, KJ ;
PREISINGER, AC ;
HEDGE, P ;
MCKECHNIE, D ;
FINNIEAR, R ;
MARKHAM, A ;
GROFFEN, J ;
BOGUSKI, MS ;
ALTSCHUL, SF ;
HORII, A ;
ANDO, H ;
MIYOSHI, Y ;
MIKI, Y ;
NISHISHO, I ;
NAKAMURA, Y .
SCIENCE, 1991, 253 (5020) :661-665
[6]   Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling [J].
Liu, WG ;
Dong, XY ;
Mai, M ;
Seelan, RS ;
Taniguchi, K ;
Krishnadath, KK ;
Halling, KC ;
Cunningham, JM ;
Qian, CP ;
Christensen, E ;
Roche, PC ;
Smith, DI ;
Thibodeau, SN .
NATURE GENETICS, 2000, 26 (02) :146-147
[7]   Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC [J].
Morin, PJ ;
Sparks, AB ;
Korinek, V ;
Barker, N ;
Clevers, H ;
Vogelstein, B ;
Kinzler, KW .
SCIENCE, 1997, 275 (5307) :1787-1790
[8]   MUTATIONS OF CHROMOSOME-5Q21 GENES IN FAP AND COLORECTAL-CANCER PATIENTS [J].
NISHISHO, I ;
NAKAMURA, Y ;
MIYOSHI, Y ;
MIKI, Y ;
ANDO, H ;
HORII, A ;
KOYAMA, K ;
UTSUNOMIYA, J ;
BABA, S ;
HEDGE, P ;
MARKHAM, A ;
KRUSH, AJ ;
PETERSEN, G ;
HAMILTON, SR ;
NILBERT, MC ;
LEVY, DB ;
BRYAN, TM ;
PREISINGER, AC ;
SMITH, KJ ;
SU, LK ;
KINZLER, KW ;
VOGELSTEIN, B .
SCIENCE, 1991, 253 (5020) :665-669
[9]   The many ways of Wnt in cancer [J].
Polakis, Paul .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2007, 17 (01) :45-51
[10]   Involvement of RNA helicases p68 and p72 in colon cancer [J].
Shin, Sook ;
Rossow, Kari L. ;
Grande, Joseph P. ;
Janknecht, Ralf .
CANCER RESEARCH, 2007, 67 (16) :7572-7578