Lipase-catalyzed kinetic resolution of Z-configured homoallylic alcohols

被引：13

作者：

Adam, W ^{[1
]}

Saha-Möller, CR ^{[1
]}

Schmid, KS ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 02期

关键词：

D O I：

10.1016/S0957-4166(98)00511-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Racemic Z homoallylic alcohols were prepared by the BuSnCl3-catalyzed addition of aldehydes to 1-(tributylstannyl)-2-butene. These alcohols were resolved for the first time by lipase-catalyzed enantioselective acetylation in up to 98% enantiomeric purity. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：315 / 322

页数：8

共 18 条

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