Rapid prototyping of multilayer thiolene microfluidic chips by photopolymerization and transfer lamination

被引:37
作者
Natali, Marco [1 ]
Begolo, Stefano [2 ]
Carofiglio, T. [3 ]
Mistura, Giampaolo [2 ]
机构
[1] CNR, ICIS, Corso Stati Uniti 4, I-35127 Padua, Italy
[2] Univ Padua, Dept Phys, I-35131 Padua, Italy
[3] Univ Padua, Dept Chem, I-35131 Padua, Italy
关键词
D O I
10.1039/b716594c
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A new fabrication process is described allowing rapid prototyping of multilayer microfluidic chips using commercial thiolene optical adhesives. Thiolene monomer liquid is photopolymerized across transparency masks to obtain partially cured patterns supported on thin polyethylene sheets. The patterns are easily laminated and transferred to a substrate due to the elastomeric nature and adhesiveness of partially cured thiolene. The process characteristics are evaluated by realizing several test structures and fluidic chips. As an example of application, the operation of a microfluidic bead array sensor for pH measurements is then described in some detail.
引用
收藏
页码:492 / 494
页数:3
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