The GTPase CpgA is implicated in the deposition of the peptidoglycan sacculus in Bacillus subtilis

被引:11
作者
Absalon, Cedric [1 ]
Hamze, Kassem [1 ]
Blanot, Didier [2 ]
Frehel, Claude [3 ]
Carballido-Lopez, Rut [4 ]
Holland, Barry I. [1 ]
van Heijenoort, Jean [2 ]
Seror, Simone J. [1 ]
机构
[1] Univ Paris 11, Inst Genet & Microbiol, CNRS, UMR 8621, F-91405 Orsay, France
[2] Univ Paris 11, Inst Biochim & Biophys Mol & Cellulaire, CNRS, UMR 8619, F-91405 Orsay, France
[3] Hop Necker Enfants Malad, Inst Natl Sante Rech Med, U 750, F-75730 Paris, France
[4] INRA, UR 895, Genet Microbienne Dynam Genom Genom Domaine Vilve, F-78352 Jouy En Josas, France
关键词
D O I
10.1128/JB.01994-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Depletion of the Bacillus subtilis GTPase CpgA produces abnormal cell shapes, nonuniform deposition of cell wall, and five- to sixfold accumulation of peptidoglycan precursors. Nevertheless, the inherent structure of the cell wall appeared mostly unchanged. The results are consistent with CpgA being involved in coordinating normal peptidoglycan deposition.
引用
收藏
页码:3786 / 3790
页数:5
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