Lipid droplets: a classic organelle with new outfits

被引：267

作者：

Fujimoto, Toyoshi ^{[1
]}

Ohsaki, Yuki ^{[1
]}

Cheng, Jinglei ^{[1
]}

Suzuki, Michitaka ^{[1
]}

Shinohara, Yuki ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Med, Dept Anat & Mol Cell Biol, Nagoya, Aichi 4668550, Japan

来源：

HISTOCHEMISTRY AND CELL BIOLOGY | 2008年 / 130卷 / 02期

关键词：

lipid droplet; lipid ester; phospholipid; cholesterol; PAT protein; caveolin;

D O I：

10.1007/s00418-008-0449-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Lipid droplets are depots of neutral lipids that exist virtually in any kind of cell. Recent studies have revealed that the lipid droplet is not a mere lipid blob, but a major contributor not only to lipid homeostasis but also to diverse cellular functions. Because of the unique structure as well as the functional importance in relation to obesity, steatosis, and other prevailing diseases, the lipid droplet is now reborn as a brand new organelle, attracting interests from researchers of many disciplines.

引用

页码：263 / 279

页数：17

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