Two New Ginkgolides from the Leaves of Ginkgo biloba

被引：37

作者：

Liao, Hua-Jun ^{[1
]}

Zheng, Yun-Feng ^{[1
]}

Li, Hong-Yang ^{[1
]}

Peng, Guo-Ping ^{[1
]}

机构：

[1] Nanjing Univ Chinese Med, Coll Pharm, Nanjing 210029, Peoples R China

来源：

PLANTA MEDICA | 2011年 / 77卷 / 16期

关键词：

Ginkgoaceae; Ginkgo biloba L; ginkgolide P; ginkgolide Q; platelet activating factor;

D O I：

10.1055/s-0030-1271153

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new diterpenoid compounds, ginkgolide P (1) and ginkgolide Q (2), were isolated from the leaves of Ginkgo biloba L. Their structures were elucidated by various spectroscopic methods, and the structure of 1 was further confirmed by X-ray crystallographic analysis. The activities of the compounds were evaluated against platelet aggregation induced by platelet activating factor (PAF), and the preliminary structure-activity relationship was also discussed.

引用

页码：1818 / 1821

页数：4

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