CO2-induced panic attacks:: A twin study

被引:59
作者
Bellodi, L [1 ]
Perna, G [1 ]
Caldirola, D [1 ]
Arancio, C [1 ]
Bertani, A [1 ]
Di Bella, D [1 ]
机构
[1] Ist Sci San Raffaele, Dept Neuropsychiat Sci, Anxiety Disorders Clin & Res Unit, I-20127 Milan, Italy
关键词
D O I
10.1176/ajp.155.9.1184
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: The authors investigated the role of genetic factors in 35% CO2-induced panic attacks. Method: Ninety twins recruited from the general population were challenged with one-vital-capacity inhalations of 35% CO2-65% O-2 Probandwise concordance rates were calculated and rates compared for monozygotic and for dizygotic twins. Results: A significantly higher concordance was found for 35% CO2-induced panic attacks among monozygotic than dizygotic twins (55.6% Versus 12.5%). Conclusions: These results suggest a relevant role of genetic factors in 35% CO2-induced panic attacks.
引用
收藏
页码:1184 / 1188
页数:5
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