Binding of a dinuclear ruthenium(II) complex to the TAR region of the HIV-AIDS viral RNA

被引：20

作者：

Buck, Damian P. ^{[1
]}

Spillane, Caitriona B. ^{[2
]}

Collins, J. Grant ^{[1
]}

Keene, F. Richard ^{[2
]}

机构：

[1] Univ New S Wales, Univ Coll, Sch Phys Environm & Math Sci, Australian Def Force Acad, Canberra, ACT 2600, Australia

[2] James Cook Univ, Sch Pharm & Mol Sci, Townsville, Qld 4811, Australia

来源：

MOLECULAR BIOSYSTEMS | 2008年 / 4卷 / 08期

关键词：

D O I：

10.1039/b803216e

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Molecular modelling has identified a new RNA conformational feature created by the insertion of bulge residues into duplex regions that may act as a recognition site for small molecule binding, in particular for inert dinuclear ruthenium complexes.

引用

页码：851 / 854

页数：4

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