ZFIN: enhancements and updates to the zebrafish model organism database

被引:174
作者
Bradford, Yvonne [1 ]
Conlin, Tom [1 ]
Dunn, Nathan [1 ]
Fashena, David [1 ]
Frazer, Ken [1 ]
Howe, Douglas G. [1 ]
Knight, Jonathan [1 ]
Mani, Prita [1 ]
Martin, Ryan [1 ]
Moxon, Sierra A. T. [1 ]
Paddock, Holly [1 ]
Pich, Christian [1 ]
Ramachandran, Sridhar [1 ]
Ruef, Barbara J. [1 ]
Ruzicka, Leyla [1 ]
Schaper, Holle Bauer [1 ]
Schaper, Kevin [1 ]
Shao, Xiang [1 ]
Singer, Amy [1 ]
Sprague, Judy [1 ]
Sprunger, Brock [1 ]
Van Slyke, Ceri [1 ]
Westerfield, Monte [1 ]
机构
[1] ZFIN, Eugene, OR 97403 USA
基金
美国国家卫生研究院;
关键词
ONTOLOGY;
D O I
10.1093/nar/gkq1077
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ZFIN, the Zebrafish Model Organism Database, http://zfin.org, serves as the central repository and web-based resource for zebrafish genetic, genomic, phenotypic and developmental data. ZFIN manually curates comprehensive data for zebrafish genes, phenotypes, genotypes, gene expression, antibodies, anatomical structures and publications. A wide-ranging collection of web-based search forms and tools facilitates access to integrated views of these data promoting analysis and scientific discovery. Data represented in ZFIN are derived from three primary sources: curation of zebrafish publications, individual research laboratories and collaborations with bioinformatics organizations. Data formats include text, images and graphical representations. ZFIN is a dynamic resource with data added daily as part of our ongoing curation process. Software updates are frequent. Here, we describe recent additions to ZFIN including (i) enhanced access to images, (ii) genomic features, (iii) genome browser, (iv) transcripts, (v) antibodies and (vi) a community wiki for protocols and antibodies.
引用
收藏
页码:D822 / D829
页数:8
相关论文
共 9 条
  • [1] An ontology for cell types
    Bard, J
    Rhee, SY
    Ashburner, M
    [J]. GENOME BIOLOGY, 2005, 6 (02)
  • [2] The Gene Ontology in 2010: extensions and refinements The Gene Ontology Consortium
    Berardini, Tanya Z.
    Li, Donghui
    Huala, Eva
    Bridges, Susan
    Burgess, Shane
    McCarthy, Fiona
    Carbon, Seth
    Lewis, Suzanna E.
    Mungall, Christopher J.
    Abdulla, Amina
    Wood, Valerie
    Feltrin, Erika
    Valle, Giorgio
    Chisholm, Rex L.
    Fey, Petra
    Gaudet, Pascale
    Kibbe, Warren
    Basu, Siddhartha
    Bushmanova, Yulia
    Eilbeck, Karen
    Siegele, Deborah A.
    McIntosh, Brenley
    Renfro, Daniel
    Zweifel, Adrienne
    Hu, James C.
    Ashburner, Michael
    Tweedie, Susan
    Alam-Faruque, Yasmin
    Apweiler, Rolf
    Auchinchloss, Andrea
    Bairoch, Amos
    Barrell, Daniel
    Binns, David
    Blatter, Marie-Claude
    Bougueleret, Lydie
    Boutet, Emmanuel
    Breuza, Lionel
    Bridge, Alan
    Browne, Paul
    Chan, Wei Mun
    Coudert, Elizabeth
    Daugherty, Louise
    Dimmer, Emily
    Eberhardt, Ruth
    Estreicher, Anne
    Famiglietti, Livia
    Ferro-Rojas, Serenella
    Feuermann, Marc
    Foulger, Rebecca
    Gruaz-Gumowski, Nadine
    [J]. NUCLEIC ACIDS RESEARCH, 2010, 38 : D331 - D335
  • [3] The Sequence Ontology: a tool for the unification of genome annotations
    Eilbeck, K
    Lewis, SE
    Mungall, CJ
    Yandell, M
    Stein, L
    Durbin, R
    Ashburner, M
    [J]. GENOME BIOLOGY, 2005, 6 (05)
  • [4] Normal Table of Postembryonic Zebrafish Development: Staging by Externally Visible Anatomy of the Living Fish
    Parichy, David M.
    Elizondo, Michael R.
    Mills, Margaret G.
    Gordon, Tiffany N.
    Engeszer, Raymond E.
    [J]. DEVELOPMENTAL DYNAMICS, 2009, 238 (12) : 2975 - 3015
  • [5] REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish development
    Plaster, Nikki
    Sonntag, Carmen
    Schilling, Thomas F.
    Hammerschmidt, Matthias
    [J]. DEVELOPMENTAL DYNAMICS, 2007, 236 (07) : 1891 - 1904
  • [6] The Zebrafish Information Network: the zebrafish model organism database
    Sprague, Judy
    Bayraktaroglu, Leyla
    Clements, Dave
    Conlin, Tom
    Fashena, David
    Frazer, Ken
    Haendel, Melissa
    Howe, Douglas G.
    Mani, Prita
    Ramachandran, Sridhar
    Schaper, Kevin
    Segerdell, Erik
    Song, Peiran
    Sprunger, Brock
    Taylor, Sierra
    Van Slyke, Ceri E.
    Westerfield, Monte
    [J]. NUCLEIC ACIDS RESEARCH, 2006, 34 : D581 - D585
  • [7] Thisse B., 2001, R01RR15402 NIH
  • [8] Linking Human Diseases to Animal Models Using Ontology-Based Phenotype Annotation
    Washington, Nicole L.
    Haendel, Melissa A.
    Mungall, Christopher J.
    Ashburner, Michael
    Westerfield, Monte
    Lewis, Suzanna E.
    [J]. PLOS BIOLOGY, 2009, 7 (11):
  • [9] The vertebrate genome annotation (Vega) database
    Wilming, L. G.
    Gilbert, J. G. R.
    Howe, K.
    Trevanion, S.
    Hubbard, T.
    Harrow, J. L.
    [J]. NUCLEIC ACIDS RESEARCH, 2008, 36 : D753 - D760