Prions: Health scare and biological challenge

被引：117

作者：

Aguzzi, A ^{[1
]}

Montrasio, F ^{[1
]}

Kaeser, PS ^{[1
]}

机构：

[1] Univ Zurich, Inst Neuropathol, CH-8091 Zurich, Switzerland

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 02期

关键词：

D O I：

10.1038/35052063

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Although human prion diseases are rare, the incidence of 'new variant' Creutzfeldt-Jakob disease in the United Kingdom is increasing exponentially. Given that this disease is probably the result of infection with bovine prions, understanding how prions replicate - and how to counteract their action - has become a central issue for public health. What are the links between the bovine and human prion diseases, and how do prions reach and damage the central nervous system?

引用

页码：118 / 126

页数：9

共 91 条

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