Nitric oxide and cancer

被引：7

作者：

Chhatwal, VJS

Moochhala, SM

Chan, STF

Ngoi, SS

机构：

[1] Department of Surgery, National University of Singapore

[2] Department of Surgery, National University of Singapore, Singapore 0511

来源：

MEDICAL HYPOTHESES | 1996年 / 46卷 / 01期

关键词：

D O I：

10.1016/S0306-9877(96)90230-3

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 [基础医学];

摘要：

The possibility that the overall process of carcinogenesis may be linked to the deficiency of nitric oxide in a biological cell is examined. A hypothetical model of how this might operate to produce subtle changes in a cell resulting in and/or facilitating carcinogenesis is suggested.

引用

收藏

页码：21 / 24

页数：4

相关论文

共 23 条

[1]

NITRIC-OXIDE - MEDIATOR, MURDERER, AND MEDICINE [J].

ANGGARD, E .

LANCET, 1994, 343 (8907) :1199-1206

[2]

NITRIC-OXIDE - NOVEL BIOLOGY WITH CLINICAL RELEVANCE [J].

BILLIAR, TR .

ANNALS OF SURGERY, 1995, 221 (04) :339-349

[3]

BUTTERY LDK, 1993, CANCER RES, V171, P311

[4]

ABERRANT EXPRESSION OF NITRIC-OXIDE SYNTHASE IN HUMAN POLYPS, NEOPLASTIC COLONIC MUCOSA AND SURROUNDING PERITUMORAL NORMAL MUCOSA [J].

CHHATWAL, VJS ;

NGOI, SS ;

CHAN, STF ;

CHIA, YW ;

MOOCHHALA, SM .

CARCINOGENESIS, 1994, 15 (10) :2081-2085

[5]

HUMAN MONOCYTES/MACROPHAGES - NO OR NO NO [J].

DENIS, M .

JOURNAL OF LEUKOCYTE BIOLOGY, 1994, 55 (05) :682-684

[6]

DONG ZY, 1994, CANCER RES, V54, P789

[7]

NITRIC-OXIDE IS AN IMPORTANT MEDIATOR FOR TUMORICIDAL ACTIVITY IN-VIVO [J].

FARIASEISNER, R ;

SHERMAN, MP ;

AEBERHARD, E ;

CHAUDHURI, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (20) :9407-9411

[8]

EPR CHARACTERIZATION OF MOLECULAR TARGETS FOR NO IN MAMMALIAN-CELLS AND ORGANELLES [J].

HENRY, Y ;

LEPOIVRE, M ;

DRAPIER, JC ;

DUCROCQ, C ;

BOUCHER, JL ;

GUISSANI, A .

FASEB JOURNAL, 1993, 7 (12) :1124-1134

[9]

NITRIC-OXIDE - A CYTO-TOXIC ACTIVATED MACROPHAGE EFFECTOR MOLECULE [J].

HIBBS, JB ;

TAINTOR, RR ;

VAVRIN, Z ;

RACHLIN, EM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 157 (01) :87-94

[10]

ENDOTHELIUM-DERIVED RELAXING FACTOR PRODUCED AND RELEASED FROM ARTERY AND VEIN IS NITRIC-OXIDE [J].

IGNARRO, LJ ;

BUGA, GM ;

WOOD, KS ;

BYRNS, RE ;

CHAUDHURI, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (24) :9265-9269