Mechanisms of disease: Systemic lupus erythematosus

被引：1402

作者：

Rahman, Anisur ^{[1
]}

Isenberg, David A. ^{[1
]}

机构：

[1] UCL, Div Med, Ctr Rheumatol Res, London W1T 4JF, England

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2008年 / 358卷 / 09期

关键词：

D O I：

10.1056/NEJMra071297

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pathogenic autoantibodies are the primary cause of tissue damage in patients with lupus. The production of these antibodies arises by means of complex mechanisms involving every key facet of the immune system. Many different elements of the system are potential targets for therapeutic drugs in patients with lupus. Copyright © 2008 Massachusetts Medical Society. All rights reserved.

引用

页码：929 / 939

页数：11

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