The endocannabinoid system in vertebrate male reproduction: A comparative overview

被引：39

作者：

Cacciola, Giovanna ^{[1
]}

Chioccarelli, Teresa ^{[1
]}

Ricci, Giulia ^{[2
]}

Meccariello, Rosaria ^{[3
]}

Fasano, Silvia ^{[1
]}

Pierantoni, Riccardo ^{[1
]}

Cobellis, Gilda ^{[1
]}

机构：

[1] Univ Naples 2, Dipartimento Med Sperimentale, Sez F Bottazzi, I-80138 Naples, Italy

[2] Univ Naples 2, Dipartimento Med Sperimentale, Sez F Bottazzi, Lab Istol, I-80138 Naples, Italy

[3] Univ Napoli Parthenope, Dipartimento Studi Ist & Sistemi Territoriali, I-80133 Naples, Italy

来源：

MOLECULAR AND CELLULAR ENDOCRINOLOGY | 2008年 / 286卷 / 1-2期

关键词：

endocannabinoids; cannabinoids; male reproductive tract; cannabinoid receptors;

D O I：

10.1016/j.mce.2008.01.004

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Prevailing studies emphasize on endocannabinoid activity in brain. However, sporadic evidences hint that endocannabinoid system controls male reproduction ranging from invertebrates to vertebrates. Although N-arachidonoylethanolamine is described in rat testis, its activity is still poorly known. Type-1 cannabinoid receptor and fatty acid amide hydrolase are particularly expressed in elongating spermatids and spermatozoa suggesting that endocannabinoids affect spermiogenesis and sperm physiology. Aim of this paper is to provide an analysis of the information available in vertebrates on male germ cell progression and sperm maturation mediated by the endocannabinoid system. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S24 / S30

页数：7

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