Strategies for electrochemical detection in immunochemistry

被引:28
作者
Centi, Sonia [1 ]
Laschi, Serena [1 ]
Mascini, Marco [1 ,2 ]
机构
[1] Univ Florence, Dipartimento Chim, I-50019 Florence, Italy
[2] Inst Nazl Biostrutture & Biosistemi, I-00136 Rome, Italy
关键词
PROSTATE-SPECIFIC ANTIGEN; LINKED-IMMUNOSORBENT-ASSAY; LABEL-FREE DETECTION; IMPEDIMETRIC IMMUNOSENSOR; AMPEROMETRIC IMMUNOSENSOR; CARBON NANOTUBES; MAGNETIC BEADS; AFLATOXIN B-1; IMPEDANCE SPECTROSCOPY; IMMUNOASSAY;
D O I
10.4155/BIO.09.106
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In this review, the current status of research in electrochemical immunosensors is considered. We primarily focus on label-free and enzyme-labeled immunosensors, and the analytical capabilities of these devices are discussed. Moreover, the use of magnetic beads as new materials for immunosensors coupled with electrochemical sensing is also described, together with the application of new molecules such as aptamers as specific biorecognition elements. Examples of the applicability of these devices in solving various analytical problems in clinical, environmental and food fields are reported. Finally, the prospects for the further development of immunosensor technologies are shown.
引用
收藏
页码:1271 / 1291
页数:21
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