The influence of infections on the development and severity of allergic disorders

被引：66

作者：

Herz, U

Lacy, P

Renz, H

Erb, K

机构：

[1] Univ Wurzburg, Ctr Infect Dis, D-97070 Wurzburg, Germany

[2] Univ Marburg Hosp, Cent Lab, Dept Clin Chem & Mol Diagnost, D-35033 Marburg, Germany

[3] Univ Alberta, Dept Med, Edmonton, AB T6G 2S2, Canada

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 06期

关键词：

D O I：

10.1016/S0952-7915(00)00155-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The frequency and severity of atopic disorders are steadily increasing, particularly in developing countries. The reason for this observation is not clear. Recent studies indicate that infections with viruses and especially with bacteria early in life may help to inhibit allergic Th2 responses by skewing the immune system towards Th1 responses. However, infections can also lead to the exacerbation of atopic disorders.

引用

页码：632 / 640

页数：9

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