Iron-catalyzed direct arylation through directed C-H bond activation

被引：334

作者：

Norinder, Jakob ^{[1
]}

Matsumoto, Arimasa ^{[1
]}

Yoshikai, Naohiko ^{[1
]}

Nakamura, Eiichi ^{[1
]}

机构：

[1] Univ Tokyo, Dept Chem, Bunkyo Ku, Tokyo 113, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 18期

关键词：

D O I：

10.1021/ja800818b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An iron-catalyzed C-C bond formation reaction of a nitrogencontaining aromatic compound with an arylzinc reagent takes place at 0 degrees C in a good to quantitative yield. The reaction involves a C-H bond activation directed by a neighboring nitrogen atom. The important additives in this reaction are 1,10-phenanthroline, tetramethylethylenediamine, and 1,2-dichloro2-methylpropane, in the absence of which a very low product yield was observed.

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页码：5858 / +

页数：3

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