In situ analysis of a mercaptoundecanoic acid layer on gold in liquid phase, by PM-IRAS.: Evidence for chemical changes with the solvent

被引：23

作者：

Méthivier, C

Beccard, B

Pradier, CM

机构：

[1] ENSCP, Lab Physico Chim Surfaces, CNRS, UMR 7045, F-75005 Paris, France

[2] Thermo Nicolet, F-91963 Courtaboeuf, France

来源：

LANGMUIR | 2003年 / 19卷 / 21期

关键词：

D O I：

10.1021/la0345789

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The in situ PM-IRAS spectra of adsorbed 11-mercaptoundecanoic acid (MUA) on gold surfaces are reported. PM-IRAS measurements were performed at 70degrees of incidence, through a 1-mum-thick layer of solvent. Spectra taken in various solvents are compared to the one recorded on a dry surface. Observed spectral changes between dry and liquid-phase spectra suggest structural changes in the adsorbed layer, correlated to chemical modifications of the thiol headgroup: deprotonation of the carboxylic groups was observed in basic aqueous or in ethanolic medium, accompanied with a progressive disorder of the chain. This effect was reversible as shown by measurements after re-immersion in a neutral aqueous solution. The use of D2O, as aqueous solvent, permitted the spectral analysis in the nu(C=O) region in neutral, acidic, and basic solutions.

引用

页码：8807 / 8812

页数：6

共 36 条

[1] Surface plasmon resonance (SPR) as a tool for antibody conjugate analysis [J].