Traceless solid-phase synthesis of substituted benzimidazoles via a base-cleavable linker

被引：73

作者：

Tumelty, D ^{[1
]}

Cao, K ^{[1
]}

Holmes, CP ^{[1
]}

机构：

[1] Affymax Res Inst, Palo Alto, CA 94304 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 01期

关键词：

D O I：

10.1021/ol006801o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A solid phase route to substituted benzimidazoles has been developed using a modified base labile linker strategy to release the final products in a traceless manner. This approach permits the synthesis of diverse compounds in moderate yields and high purity.

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页码：83 / 86

页数：4

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