Priming the hematopoietic pump

被引：28

作者：

Orkin, SH ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Howard Hughes Med Inst, Dana Farber Canc Inst, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Howard Hughes Med Inst, Childrens Hosp, Boston, MA 02115 USA

来源：

IMMUNITY | 2003年 / 19卷 / 05期

关键词：

D O I：

10.1016/S1074-7613(03)00302-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Markers of multiple hematopoietic lineages are expressed in multipotent progenitors, a phenomenon referred to as lineage priming." A new study in this issue of Immunity provides compelling evidence that such "promiscuous" gene expression occurs in hematopoietic stem cells and does not interfere with their long-term repopulation potential."

引用

页码：633 / 634

页数：2

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