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MEDICAL PROGRESS Acute HIV-1 Infection

被引：462
作者：
Cohen, Myron S. [1 ]
Shaw, George M. [3 ]
McMichael, Andrew J. [4 ,5 ]
Haynes, Barton F. [2 ]
机构：
[1] Univ N Carolina, Inst Global Hlth & Infect Dis, Chapel Hill, NC USA
[2] Duke Univ, Sch Med, Duke Human Vaccine Inst, Durham, NC USA
[3] Univ Alabama Birmingham, Birmingham, AL USA
[4] Univ Oxford, Weatherall Inst Mol Med, Oxford, England
[5] Univ Oxford, Natl Inst Hlth Res, Biomed Res Ctr, Oxford, England
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2011年 / 364卷 / 20期
基金：
美国国家卫生研究院;
关键词：
IMMUNODEFICIENCY-VIRUS TYPE-1; CD4(+) T-CELLS; ANTIRETROVIRAL THERAPY; SEXUAL TRANSMISSION; INTEGRIN ALPHA(4)BETA(7); PARTNER NOTIFICATION; RESPONSES; STAGE; SIV; VIREMIA;
D O I：
10.1056/NEJMra1011874
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
IN 2009, THE UNITED NATIONS ESTIMATED THAT 33.2 MILLION PEOPLE worldwide were living with human immunodeficiency virus type 1 (HIV-1) infection and that 2.6 million people had been newly infected.(1) The need for effective HIV-1 prevention has never been greater. In this review, we address recent critical advances in our understanding of HIV-1 transmission and acute HIV-1 infection. Fourth-generation HIV-1 testing, now available worldwide,(2,3) will allow the diagnosis of infection in many patients and may lead to new treatments and opportunities for prevention.
引用
收藏
页码：1943 / 1954
页数：12
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