Facile O-arylation of phenols and carboxylic acids

被引：123

作者：

Liu, ZJ ^{[1
]}

Larock, RC ^{[1
]}

机构：

[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 01期

关键词：

D O I：

10.1021/ol0361406

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile, transition-metal-free O-arylation procedure for phenols and aromatic carboxylic acids has been developed that affords good to excellent yields of arylated products under very mild reaction conditions. A methoxy-substituted aryl triflate affords O-arylated products in high yields with excellent regioselectivity. This chemistry tolerates a variety of functional groups.

引用

页码：99 / 102

页数：4

共 35 条

[21] STUDIES ON SELECTIVE NUCLEOPHILIC-SUBSTITUTION REACTIONS OF [(CYCLOPENTADIENYL)(1,3-DICHLOROBENZENE)M]+ PF6(-) COMPLEXES (M = FE, RU)
PEARSON, AJ
PARK, JG
ZHU, PY
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (13) : 3583 - 3589
[22] STUDIES ON THE SYNTHESIS OF ARYL ETHERS USING ARENE-MANGANESE CHEMISTRY
PEARSON, AJ
BRUHN, PR
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (25) : 7092 - 7097
[23] Palladium-catalyzed cocyclization of arynes with alkynes:: Selective synthesis of phenanthrenes and naphthalenes
Peña, D
Pérez, D
Guitián, E
Castedo, L
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (24) : 5827 - 5828
[24] ANTINEOPLASTIC AGENTS .160. ISOLATION AND STRUCTURE OF COMBRETASTATIN-D-1 - A CELL-GROWTH INHIBITORY MACROCYCLIC LACTONE FROM COMBRETUM-CAFFRUM
PETTIT, GR
SINGH, SB
NIVEN, ML
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (25) : 8539 - 8540
[25] Ramesh C, 2002, SYNTHESIS-STUTTGART, P2171
[26] Sawyer JS, 2000, TETRAHEDRON, V56, P5045
[27] AROMATIC POLYETHER SYNTHESIS VIA ACTIVATED SUBSTITUTION IN A RUTHENIUM(II) COMPLEX OF PARA-DICHLOROBENZENE
SEGAL, JA
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1985, (19) : 1338 - 1339
[28] Seldon R. A., 1998, CHIROTECHNOLOGY, P62
[29] ANTINEOPLASTIC AGENTS .206. STRUCTURE OF THE CYTOSTATIC MACROCYCLIC LACTONE COMBRETASTATIN-D-2
SINGH, SB
PETTIT, GR
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (09) : 2797 - 2800
[30] Theil F, 1999, ANGEW CHEM INT EDIT, V38, P2345, DOI 10.1002/(SICI)1521-3773(19990816)38:16<2345::AID-ANIE2345>3.0.CO

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