DO WE NEED MORE HUMAN EMBRYONIC STEM CELL LINES?

被引:8
作者
Arabadjiev, B. [1 ,2 ]
Petkova, R. [2 ]
Chakarov, S. [1 ,2 ]
Momchilova, A. [3 ]
Pankov, R. [1 ]
机构
[1] Sofia Univ St Kliment Ohridsky, Fac Biol, Dept Cytol Histol & Embryol, Sofia, Bulgaria
[2] Sci Technol Serv Ltd, Sofia, Bulgaria
[3] Bulgarian Acad Sci, Inst Biophys, Sofia, Bulgaria
关键词
embryonic stem cells; induced pluripotent stem cells; GENE-EXPRESSION; DERIVATION; HLA; PLURIPOTENCY; GENERATION; EFFICIENCY; DIVERSITY;
D O I
10.2478/V10133-010-0071-X
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要
The enormous potential of human embryonic stem cells is fueling continuous research aimed at establishment of new lines of these cells. Currently research groups from 24 countries have reported derivation of over 1000 human embryonic stem cell lines. Because of the controversy surrounding the derivation of these cells from human embryos it is important to clarify whether the existing hESC lines are sufficient for basic research and future therapeutic applications. Here we briefly review some of the most important arguments justifying the need for continuing derivation of human embryonic stem cell lines.
引用
收藏
页码:1921 / 1927
页数:7
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