Synthesis of branched oligonucleotides as templates for the assembly of nanomaterials

被引：19

作者：

Grimau, MG

Iacopino, D

Aviño, A

de la Torre, BG

Ongaro, A

Fitzmaurice, D

Wessels, J

Eritja, R

机构：

[1] CSIC, Inst Biol Mol Barcelona, Dept Biol Struct, E-08034 Barcelona, Spain

[2] Univ Coll Dublin, Dept Chem, Dublin 4, Ireland

[3] Sony Int Europe GmbH, Adv Technol Ctr Stuttgart, D-70327 Stuttgart, Germany

来源：

HELVETICA CHIMICA ACTA | 2003年 / 86卷 / 08期

关键词：

D O I：

10.1002/hlca.200390232

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Branched oligonucleotides with symmetric arms 6-15, which may contain biotin as a second recognition code, were prepared. These molecules are designed to be used for the directed assembly of nanomaterials. The branched structure of the desired oligonucleotides was confirmed by mass spectrometry on small branched oliognucleotides, by gel electrophoresis, and by hybridization with complementary oligonucleotide-nanoparticle conjugates, followed by visualization of the complexes by transmission electron microscopy.

引用

收藏

页码：2814 / 2826

页数：13

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