Murihexol, a linear acetogenin from Annona muricata

被引：14

作者：

Yu, JG ^{[1
]}

Gui, HQ

Luo, XZ

Sun, L

机构：

[1] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China

[2] Peking Union Med Coll, Beijing 100094, Peoples R China

来源：

PHYTOCHEMISTRY | 1998年 / 49卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Annona muricata; Annonaceae; seeds; acetogenins; murihexol;

D O I：

10.1016/S0031-9422(98)00224-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Murihexol (1), a novel acetogenin, and three known ones, donhexocin (2), annonacin A and annonacin, have been isolated from the seeds of Annona muricata. Compound 1 is a C-35 acetogenin without any THF rings, with six hydroxyls in the long aliphatic chain. The hydroxyls of 1 and 2 are all located at C-4, C-IO, C-15, C-16, C-19 and C-20, but their stereochemistries are different. The vicinal diol at C-15/ C-16 in 1 is threo and C-19/C-20 has the erythro configuration; in 2 C-15/C-16 and C-19/C-20 all have the same threo configuration. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1689 / 1692

页数：4

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