Peroxide-promoted regioselective arylation of 2-phenylpyridines and related substrates with aryl iodides

被引：40

作者：

Cheng, Kai ^{[1
]}

Zhang, Yuhong ^{[1
]}

Zhao, Jinlong ^{[1
]}

Xie, Chunsong ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

SYNLETT | 2008年 / 09期

关键词：

C-H activation; arylation; ruthenium homogeneous catalysis;

D O I：

10.1055/s-2008-1072765

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The direct arylation of aryl iodides with 2-phenylpyridines and related substrates was carried out smoothly in the presence of 5 mol% RuCl3 using benzoyl peroxide as a promoter to generate biarylated products in high yields. The method is simple, efficient, and regioselective, and employs only commercially available reagents.

引用

页码：1325 / 1330

页数：6

共 33 条

[31] Synthesis of indolo[1,2-f]phenanthridines from palladium-catalyzed reactions of arynes [J].

Xie, Chunsong ;

Zhang, Yuhong ;

Huang, Zedu ;

Xu, Peixin .

JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (14) :5431-5434

[32] Carbon-carbon coupling reactions catalyzed by heterogeneous palladium catalysts [J].

Yin, Lunxiang ;

Liebscher, Juergen .

CHEMICAL REVIEWS, 2007, 107 (01) :133-173

[33] Highly regloselective arylation of Sp3 C-H bonds catalyzed by palladium acetate [J].

Zaitsev, VG ;

Shabashov, D ;

Daugulis, O .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (38) :13154-13155

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