An efficient and facile one-pot synthesis of cyanohydrin esters from carbonyl compounds catalyzed by iron(III) chloride

被引：40

作者：

Iwanami, K ^{[1
]}

Aoyagi, M ^{[1
]}

Oriyama, T ^{[1
]}

机构：

[1] Ibaraki Univ, Fac Sci, Mito, Ibaraki 3108512, Japan

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 44期

关键词：

cyanation; cyanohydrin ester; trimethylsilyl cyanide; acid anhydride; carbonyl compound; iron(III) chloride;

D O I：

10.1016/j.tetlet.2005.09.003

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of cyanohydrin esters were readily prepared from carbonyl compounds with trimethylsilyl cyanide and acid anhydride under the influence of a catalytic amount of iron(III) chloride in a convenient one-pot procedure. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：7487 / 7490

页数：4

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