MiRNA in embryonic development: The taming of nodal signaling

被引：7

作者：

Collignon, Jerome ^{[1
]}

机构：

[1] Univ Paris 07, F-75221 Paris 05, France

[2] Univ Paris 07, F-75221 Paris, France

[3] Inst Jacques Monod, Dept Dev Biol, CNRS, F-75251 Paris 05, France

来源：

DEVELOPMENTAL CELL | 2007年 / 13卷 / 04期

关键词：

D O I：

10.1016/j.devcel.2007.09.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The TGF-beta family member Nodal is one of the most potent molecules known to an embryo. Studies on Nodal regulation thus far have focused on its transcription, maturation, and interaction with antagonists. Two recent studies on the role of microRNAs (miRNAs) in Nodal signaling now reveal that something important was missing from the picture.

引用

页码：458 / 460

页数：3

共 8 条

[1] Dicer is essential for mouse development [J].

Bernstein, E ;

Kim, SY ;

Carmell, MA ;

Murchison, EP ;

Alcorn, H ;

Li, MZ ;

Mills, AA ;

Elledge, SJ ;

Anderson, KV ;

Hannon, GJ .

NATURE GENETICS, 2003, 35 (03) :215-217

[2]

BUSHATI N, 2007, IN PRESS ANN REV CEL

[3]

CHOI WY, 2007, IN PRESS SCIENCE

[4] Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs [J].

Giraldez, AJ ;

Mishima, Y ;

Rihel, J ;

Grocock, RJ ;

Van Dongen, S ;

Inoue, K ;

Enright, AJ ;

Schier, AF .

SCIENCE, 2006, 312 (5770) :75-79

[5] MicroRNAs regulate brain morphogenesis in zebrafish [J].

Giraldez, AJ ;

Cinalli, RM ;

Glasner, ME ;

Enright, AJ ;

Thomson, JM ;

Baskerville, S ;

Hammond, SM ;

Bartel, DP ;

Schier, AF .

SCIENCE, 2005, 308 (5723) :833-838

[6] MicroRNA control of nodal signalling [J].

Martello, Graziano ;

Zacchigna, Luca ;

Inui, Masafumi ;

Montagner, Marco ;

Adorno, Maddalena ;

Mamidi, Anant ;

Morsut, Leonardo ;

Soligo, Sandra ;

Tran, Uyen ;

Dupont, Sirio ;

Cordenonsi, Michelangelo ;

Wessely, Oliver ;

Piccolo, Stefano .

NATURE, 2007, 449 (7159) :183-U1

[7] Nodal signaling: developmental roles and regulation [J].

Shen, Michael M. .

DEVELOPMENT, 2007, 134 (06) :1023-1034

[8] Maternal microRNAs are essential for mouse zygotic development [J].

Tang, Fuchou ;

Kaneda, Masahiro ;

O'Carroll, Donal ;

Hajkova, Petra ;

Barton, Sheila C. ;

Sun, Y. Andrew ;

Lee, Caroline ;

Tarakhovsky, Alexander ;

Lao, Kaiqin ;

Surani, M. Azim .

GENES & DEVELOPMENT, 2007, 21 (06) :644-648

← 1 →