Anti-HIV coumarins from Calophyllum seed oil

被引：296

作者：

Spino, C

Dodier, M

Sotheeswaran, S

机构：

[1] Univ Sherbrooke, Dept Chim, Sherbrooke, PQ J1K 2R1, Canada

[2] Univ S Pacific, Sch Pure & Appl Sci, Suva, Fiji

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 24期

关键词：

D O I：

10.1016/S0960-894X(98)00628-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The seeds of Calophyllum cerasiferum Vesque (Family Clusiaceae), and Calophyllum inophyllum Linn. (Family - Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：3475 / 3478

页数：4

相关论文

共 9 条

[1] ANALYSIS OF NONNUCLEOSIDE DRUG-RESISTANT VARIANTS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE [J].

BOYER, PL ;

CURRENS, MJ ;

MCMAHON, JB ;

BOYD, MR ;

HUGHES, SH .

JOURNAL OF VIROLOGY, 1993, 67 (04) :2412-2420

[2] RESOLUTION AND COMPARATIVE ANTI-HIV EVALUATION OF THE ENANTIOMERS OF CALANOLIDE-A AND CALANOLIDE-B [J].

CARDELLINA, JH ;

BOKESCH, HR ;

MCKEE, TC ;

BOYD, MR .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (09) :1011-1014

[3] SYNTHESIS OF OPTICALLY-ACTIVE CALANOLIDE-A AND CALANOLIDE-B [J].

DESHPANDE, PP ;

TAGLIAFERRI, F ;

VICTORY, SF ;

YAN, SJ ;

BAKER, DC .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (10) :2964-2965

[4] Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers [J].

Flavin, MT ;

Rizzo, JD ;

Khilevich, A ;

Kucherenko, A ;

Sheinkman, AK ;

Vilaychack, V ;

Lin, L ;

Chen, W ;

Greenwood, EM ;

Pengsuparp, T ;

Pezzuto, JM ;

Hughes, SH ;

Flavin, TM ;

Cibulski, M ;

Boulanger, WA ;

Shone, RL ;

Xu, ZQ .

JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (06) :1303-1313

[5] HIV-INHIBITORY COUMARINS FROM LATEX OF THE TROPICAL RAIN-FOREST TREE CALOPHYLLUM-TEYSMANNII VAR INOPHYLLOIDE [J].

FULLER, RW ;

BOKESCH, HR ;

GUSTAFSON, KR ;

MCKEE, TC ;

CARDELLINA, JH ;

MCMAHON, JB ;

CRAGG, GM ;

SOEJARTO, DD ;

BOYD, MR .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (16) :1961-1964

[6] A SEMIAUTOMATED MULTIPARAMETER APPROACH FOR ANTI-HIV DRUG SCREENING [J].

GULAKOWSKI, RJ ;

MCMAHON, JB ;

STALEY, PG ;

MORAN, RA ;

BOYD, MR .

JOURNAL OF VIROLOGICAL METHODS, 1991, 33 (1-2) :87-100

[7] HIV INHIBITORY NATURAL-PRODUCTS .7. THE CALANOLIDES, A NOVEL HIV-INHIBITORY CLASS OF COUMARIN DERIVATIVES FROM THE TROPICAL RAIN-FOREST TREE, CALOPHYLLUM-LANIGERUM [J].

KASHMAN, Y ;

GUSTAFSON, KR ;

FULLER, RW ;

CARDELLINA, JH ;

MCMAHON, JB ;

CURRENS, MJ ;

BUCKHEIT, RW ;

HUGHES, SH ;

CRAGG, GM ;

BOYD, MR .

JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (15) :2735-2743

[8]

Parham, 1972, PLANTS FIJI ISLANDS

[9]

WHISTLER WA, 1992, POLYNESIAN HERBAL ME, P129