A highly regular fraction of a fucoidan from the brown seaweed Fucus distichus L.

被引：206

作者：

Bilan, MI ^{[1
]}

Grachev, AA ^{[1
]}

Ustuzhanina, NE ^{[1
]}

Shashkov, AS ^{[1
]}

Nifantiev, NE ^{[1
]}

Usov, AI ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia

来源：

CARBOHYDRATE RESEARCH | 2004年 / 339卷 / 03期

基金：

俄罗斯基础研究基金会;

关键词：

fucoidan; NMR; disaccharide repeating unit; seaweed; brown algae; Fucus distichus;

D O I：

10.1016/j.carres.2003.10.028

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A fucoidan fraction consisting Of L-fucose, sulfate, and acetate in a molar proportion of 1:1.21:0.08 was isolated from the brown seaweed Fucus distichus collected from the Barents Sea. The C-13 NMR spectrum of the fraction was typical of regular polysaccharides containing disaccharide repeating units. According to 1D and 2D H-1 and 13 C NMR spectra, the fucoidan molecules are built up of alternating 3-linked alpha-L-fucopyranose 2,4-disulfate and 4-linked alpha-L-fucopyranose 2-sulfate residues: --> 3)-alpha-L-Fucp-(2,4-di-SO3-)-(1 --> 4)-alpha-L-Fucp-(2SO(3)(-))-(1 -->. The regular structure may be only slightly masked by random acetylation and undersulfation of several disaccharide repeating units. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：511 / 517

页数：7

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